The Health Diva

A biochanin-enriched isoflavone from red clover lowers LDL cholesterol in men. Nestel P et al. Eur J Clin Nutr. 2004 Mar;58(3):403-8

Absorption in humans of isoflavones from soy and red clover is similar. Tsunoda N, Pomeroy S, Nestel P. J Nutr 2002 Aug;132(8):2199-201

Alternative treatments for menopause symptoms. Systematic review of scientific and lay literature. Seidl MM, Stewart DE. Can Fam Physician. 1998 Jun;44:1299-308

Antioxidant activity of phytoestrogenic isoflavones. Ruiz-Larrea MB et al. Free Radic Res. 1997 Jan;26(1):63-70

Antioxidant and antipromotional effects of the soybean isoflavone genistein. Wei H et al. Proc Soc Exp Bio Med 1995 Jan; 208(1)124-130

Beneficial effect of soy isoflavones on bone mineral content was modified by years since menopause, body weight, and calcium intake: a double-blind, randomized, controlled trial. Chen, Yu-ming et al. Menopause. 11(3):246-254, 2004

Bioavailability of Isoflavones after Ingestion of Soy Beverages in Healthy Adults. Mitsuyoshi Kano, Tomomi Takayanagi, Katsuhisa Harada, Seigo Sawada and Fumiyasu Ishikawa. J. Nutr. 136:2291-2296, September 2006

Biological effects of a diet of soy protein rich in isoflavones on the menstrual cycle of premenopausal women. Cassidy A, Bingham S, Setchell KD. Am J Clin Nutr. 1994 Sep;60(3):333-40

Breast and Uterine Effects of Soy Isoflavones and Conjugated Equine Estrogens in Postmenopausal Female Monkeys. Charles E. Wood et al. The Journal of Clinical Endocrinology & Metabolism Vol. 89, No. 7 3462-3468

Chemoprevention by Grape Seed Extract and Genistein in Carcinogen-induced Mammary Cancer in Rats Is Diet Dependent. Kim H, Hall P, Smith M, Kirk M, Prasain JK, Barnes S, Grubbs C.. J. of Nutr. 2004 Dec;134(12):3445S-52S

Chemoprevention of Breast Cancer, Proteomic Discovery of Genistein Action in the Rat Mammary Gland. Craig Rowell, D. Mark Carpenter and Coral A. Lamartiniere. Journal of Nutrition, 135:2953S-2959S, December 2005

Daidzein is more efficient than genistein in preventing ovariectomy-induced bone loss in rats. Picherit C, Coxam V, Bennetau-Pelissero C, Kati-Coulibaly S, Davicco MJ, Lebecque P and Barlet JP.. J Nutr. 2000 Jul;130(7):1675-81

Dietary isoflavones: biological effects and relevance to human health. Setchell KD, Cassidy A. J Nutr. 1999 Mar;129(3):758S-767S

Dietary Soy Isoflavones and Estrone Protect Ovariectomized ERKO and Wild-Type Mice from Carcinogen-Induced Colon Cancer. Ju-Yuan Guo, Xiaosong Li, Jimmy D. Browning, Jr., George E. Rottinghaus, Dennis B. Lubahn, Andreas Constantinou, Maurice Bennink and Ruth S. MacDonald . Journal of Nutrition:179-182, January 2004

Dietary soybean protein prevents bone loss in an ovariectomized rat model of osteoporosis. Arjmandi BH et all. J Nutr. 1996 Jan;126(1):161-7

Effect of a phytoestrogen food supplement on reproductive health in normal males. Mitchell JH, Cawood E, Kinniburgh D, Provan A, Collins AR, Irvine DS. Clin Sci (Lond). 2001 Jun;100(6):613-8

Effects of a soy milk supplement on plasma cholesterol levels and oxidative DNA damage in men–a pilot study. Mitchell JH, Collins AR. Eur J Nutr. 1999 Jun;38(3):143-8

Effects of Estrogen-Progestin on Risk of Fracture and Bone Mineral Density. Jane A. Cauley, John Robbins, Zao Chen, Steven R. Cummings, Rebecca D. Jackson, Andrea Z. LaCroix, Meryl LeBoff, Cora E. Lewis, Joan McGowan, Joan Neuner, Mary Pettinger, Marcia L. Stefanick, Jean Wactawski-Wende, Nelson B. Watts. JAMA. 2003;290:1729-1738

Effects of Phytoestrogens on Bone Turnover in Postmenopausal Women with a History of Breast Cancer. Eini Nikander, Merja Metsä-Heikkilä, Olavi Ylikorkala and Aila Tiitinen . The Journal of Clinical Endocrinology and Metabolism Vol. 89, No. 3 1207-1212

Environmental Influence on Isoflavones and Saponins in Soybeans and Their Role in Colon Cancer. Ruth S. MacDonald et al. Journal of Nutrition 135: 1239-1242, 2005

Exposure to soy-based formula in infancy and endocrinological and reproductive outcomes in young adulthood.. Strom BL, Schinnar R, Ziegler EE, Barnhart KT, Sammel MD, Macones GA, Stallings VA, Drulis JM, Nelson SE and Hanson SA . JAMA. 2001 Aug 15;286(7):807-14

Factors Affecting the Bioavailability of Soy Isoflavones in Humans after Ingestion of Physiologically Relevant Levels from Different Soy Foods. Aedin Cassidy, Jonathan E. Brown, Anne Hawdon, Marian S. Faughnan, Laurence J. King, Joe Millward, Linda Zimmer-Nechemias, Brian Wolfe and Kenneth D.R. Setchell. J. Nutr. 136:45-51, January 2006

Influences of dietary soy isoflavones on metabolism but not nociception and stress hormone responses in ovariectomized female rats. Lihong Bu, Kenneth DR Setchell, and Edwin D Lephart. Reprod Biol Endocrinol. 2005; 3: 58