Sytrinol
Sytrinol is a patented and proprietary formula derived from natural citrus and palm fruit extracts. It combines polymethoxylated flavones (PMFs), delta, gamma, and alpha tocotrienols and other proprietary ingredient components.
Multiple clinical trials have demonstrated that Sytrinol acts synergistically to significantly improve total cholesterol, LDL cholesterol, and triglycerides up to 30%, 27%, and 34%, respectively, compared to placebo. Sytrinol has also been shown to increase HDL levels. Additionally, Sytrinol is a powerful anti-oxidant with numerous heart health benefits including the reduction of arterial plaque, improved glycemic control and reduced blood platelet aggregation.
Sytrinol works in the following areas:
• Cholesterol Reduction –Polymethoxylated flavones (PMFs) decrease apoprotein b, a structural protein needed for endogenous synthesis of LDL (BAD) cholesterol. Tocotrienols inhibit HMG CoA reductase, a liver enzyme responsible for endogenous synthesis of cholesterol.
Sytrinol is currently being tested , after Only the first 12 weeks (Phase 1) of the long-term study, the are already results are proving to be compelling. Compared to placebo, total cholesterol was reduced 30%, LDL cholesterol was reduced 27% and total triglycerides dropped 33%. Additionally, HDL (Good) cholesterol levels increased by 4%, resulting in a significant reduction in the LDL/HDL ratio of 30%.
• Triglyceride Lowering - PMFs (tangeretin and nobiletin) decrease diacylglycerolacetyl transferase, a liver enzyme needed for the production of triglycerides.
• Antioxidant – Sytrinol is a powerful antioxidant with numerous heart health benefits including the reduction of arterial plaque, improved glycaemic control and reduced blood platelet aggregation. A recent study that was published in the Journal of Atherosclerosis, revealed that tocotrienols were more effective than Vitamin E in reducing the expression of adhesion molecules which leads to plaque formation. The study revealed that tocotrienols accumulate at levels which are 25-95 times greater that alpha tocopherol in human aortic endothelial cells.
• Anti-Inflammatory – Recent research has established that inflammation may cause C-reactive protein (CRP) to be produced in the body. Specific PMFs, including nobiletin and tangeretin, have been studied for their anti-inflammatory properties, suggesting that the PMFs found in Sytrinol would have a positive effect on regulating CRP levels.
• Cell protective –- polymethoxylated flavones (PMFs) have been shown to possess especially potent anti-cancer and immuno-supportive benefits. Early studies revealed that nobiletin significantly inhibits production of nitric oxide (NO) and superoxide (O2-), two powerful free radicals involved in promoting inflammation and cancer. Tangeretin has been found to exert antioxidant and neuro-protective benefits and actually cross the blood-brain barrier and protect brain cells (hypothalamus, striatum and hippocampus).
• Glycaemic Control -As well as proving to be a novel cholesterol and triglyceride lowering supplement, Sytrinol also improves glycaemic control in individuals with metabolic syndrome as presented at the Canadian Federation of Biological Societies 48th Annual Meeting in Guelph, Ontario. Administration of Sytrinol compared to placebo was associated with more pronounced tendency to improved insulin responses (including 17% reduction of postprandial insulin peak, 11% reduction in insulin area curve under the curve and 53% delay in the time of insulin peak appearance) and with the less pronounced positive effect on glucose profile (43% delay in glucose peak appearance without changes in postprandial glucose concentrations). The observed beneficial effects were significantly correlated with the subject’s body mass index (BMI).
Are there any possible side effects or precautions?
Sytrinol appears to be well tolerated, and at this time there are no know side effects.
If pregnant or lactating it is always recommended to consult your doctor or health practitioner for more information.
Are there any potential drug interactions?
Sytrinol may react with blood thinning medications such as warfarin. Always consult your doctor before combining sytrinol with prescribed medications.

